电脑殷勤 发表于 2025-10-28 16:02:35

近期大量上市!这种网红水果与多种药物“相冲”,医生提醒

<!----><style type="text/css">html{font-size:375%}</style><link href="https://pics-app.cnyw.net/static/publish/css/style.css?v=20240712" rel="stylesheet" position="1" data-qf-origin="/static/publish/css/style.css?v=20240712"><!--    付费贴-->    <div class="preview_article ">            <!---->    <section style="box-sizing: border-box; font-style: normal; font-weight: 400; text-align: justify; font-size: 16px; color: #3e3e3e;"><section style="text-align: center; margin: 0px 0%; line-height: 0; box-sizing: border-box;"><section class="empty_paragraph" style="max-width: 100%; vertical-align: middle; line-height: 0; box-sizing: border-box;"></section></section><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;">&nbsp;</p><p>眼下柚类水果大量上市,酸甜多汁的&ldquo;柚味&rdquo;很多人喜欢。目前市面上售卖的带&ldquo;柚&rdquo;字的水果有很多种,沙田柚、青柚、红蜜柚、文旦柚、胡柚、葡萄柚、西柚&hellip;&hellip;</p><p>&nbsp;</p><section style="text-align: center;"><img class="rich_pages wxw-img" style="width: 677px !important; height: auto !important; visibility: visible !important;" src="https://pics-app.cnyw.net/Fi-QxbSdId2LEb-Ea6Bb6Eis31qL" alt="图片" /></section><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">需要注意的是:在服用某些药物时同时吃&ldquo;柚味&rdquo;,药效可能&ldquo;失控&rdquo;,甚至带来健康风险。</span></p><p>&nbsp;</p><p style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">01&nbsp;</span></p><p style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">吃&ldquo;柚&rdquo;</span></p><p style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">要注意</span><span style="font-size: 18px; color: #007aaa; font-weight: bold;">这些事</span></p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">柚子,尤其是西柚中</span><span style="color: #7b0c00; font-weight: bold;">含有</span><span style="color: #7b0c00; font-weight: bold;">呋喃香豆素类物质,这种成分会抑制肝脏里一种酶</span>(一种名为CYP3A4的药物代谢酶,小肠黏膜中也有)。而我们<span style="color: #7b0c00; font-weight: bold;">吃的很多药物,都需要靠这种酶来代谢分解&mdash;&mdash;酶被抑制后</span>,药物没法正常&ldquo;消化&rdquo;,就会在血液里越积越多,<span style="color: #7b0c00; font-weight: bold;">相当于&ldquo;过量服药&rdquo;</span>,副作用风险自然大幅升高。</p><p>&nbsp;</p><p>需要注意的是:<span style="color: #7b0c00; font-weight: bold;">对药物代谢影响最明确、证据最充分的是&ldquo;西柚/葡萄柚&rdquo;</span>,而不是我们中秋常见的&ldquo;柚子/蜜柚/文旦/沙田柚&rdquo;。</p><p>&nbsp;</p><section><img class="rich_pages wxw-img" style="width: 677px !important; height: auto !important; visibility: visible !important;" src="https://pics-app.cnyw.net/FuJsAvxc5qpz5fGLVSTbl5iiGuj5" alt="图片" /></section><p>&nbsp;</p><p>正确吃柚子,首先我们要注意:</p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">1、看清名称:</span>写&ldquo;西柚/葡萄柚&rdquo;或&ldquo;grapefruit juice&rdquo;的药品说明书,务必严格回避;&ldquo;柚子/蜜柚&rdquo;不是&ldquo;西柚&rdquo;。</p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">2、拿不准就当&ldquo;西柚&rdquo;处理:</span>市场上部分果汁/饮料标注不清,若无法确认,按&ldquo;西柚&rdquo;口径避开更安全。</p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">3、服药期间更要谨慎:</span>西柚的影响可持续24&ndash;72小时,错开几小时未必能完全避免相互作用。</p><p>&nbsp;</p><p style="text-align: center;"><span style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">02&nbsp;</span></span></p><p style="text-align: center;"><span style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">这几类药</span></span></p><p style="text-align: center;"><span style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">千万别和&ldquo;西柚/葡萄柚&rdquo;一起吃</span></span></p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">(1)降压药(部分钙拮抗剂):</span>可能让血压过低引发头晕/站立不稳</p><p>&nbsp;</p><p>硝苯地平(心痛定、拜新同等)</p><p>&nbsp;</p><p>非洛地平(波依定等)</p><p>&nbsp;</p><p>氨氯地平(部分复方含此成分,具个体差异、遵医嘱监测)</p><p>&nbsp;</p><p>与西柚同服可能导致血药浓度升高、血压骤降,出现头晕、乏力、心悸等。</p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">(2)降脂药(部分他汀):</span>可能加重肌病/肝损伤风险</p><p>&nbsp;</p><p>阿托伐他汀(立普妥)</p><p>&nbsp;</p><p>辛伐他汀(舒降之)</p><p>&nbsp;</p><p>洛伐他汀(美降之)</p><p>&nbsp;</p><p>这类药本身就有肌肉疼痛、肝损伤的风险,和西柚同服后,药物浓度升高,风险会翻倍:可能出现肌肉酸痛、无力,甚至引发横纹肌溶解症,同时肝脏负担也会加重。可与医生讨论替代:普伐他汀、瑞舒伐他汀,这两种同类药物受代谢酶影响较小。</p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">(3)部分抗过敏药(老药为主):</span>可能明显加重嗜睡/心律风险</p><p>&nbsp;</p><p>特非那定(敏迪)</p><p>&nbsp;</p><p>阿司咪唑(息斯敏,现已被更新药物替代,但仍需警惕旧药)</p><p>&nbsp;</p><p>这类药本身就可能引起嗜睡,和西柚同服后,药效增强,嗜睡感会明显加重,开车、操作机器时极易发生危险。</p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">(4)免疫抑制剂:</span>对浓度极其敏感,波动会带来严重后果</p><p>&nbsp;</p><p>环孢素(新山地明等)</p><p>&nbsp;</p><p>他克莫司(普乐可复等)</p><p>&nbsp;</p><p>与西柚同服可使药物在体内浓度显著变化,过高增加肾毒性/神经毒性,过低则免疫抑制不足。建议严格回避西柚及其制品。</p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">(5)镇静催眠/麻醉前用药:</span>可能&ldquo;睡过头&rdquo;甚至呼吸抑制</p><p>&nbsp;</p><p>咪达唑仑(短期助眠/麻醉前镇静)</p><p>&nbsp;</p><p>地西泮(安定,可能受影响)</p><p>&nbsp;</p><p>与西柚同服会延缓代谢、延长作用时间,老年人或呼吸功能较差者风险更高。</p><p>&nbsp;</p><p style="text-align: center;"><span style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">03</span></span></p><p style="text-align: center;"><span style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">3个实用提醒</span></span></p><p style="text-align: center;"><span style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">帮你避开风险</span></span></p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">吃药前先&ldquo;两看&rdquo;:</span>看说明书&ldquo;药物相互作用&rdquo;是否写明避免&ldquo;西柚/葡萄柚&rdquo;;再看药品通用名,是否属于前面提到的高风险药物类别。</p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">不确定就&ldquo;问&rdquo;:</span>分不清自己吃到的是&ldquo;西柚&rdquo;还是&ldquo;柚子&rdquo;,或不清楚药物是否受影响,第一时间咨询医生/药师。</p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">更安全的替代:</span>特别爱吃柚味但正在用高风险药(并非所有药都会受西柚影响,主要涉及强CYP3A4底物且首过代谢显著的口服药),如不确定,请咨询医生/药师。饮食上可选择橙、橘、苹果等通常更安全的水果。</p><p>&nbsp;</p><p style="text-align: center;"><span style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">04</span></span></p><p style="text-align: center;"><span style="text-align: center;"><span style="font-size: 18px; color: #007aaa; font-weight: bold;">常见误区问答</span></span></p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">1、西柚味饮料/果酱/酸奶算不算?</span></p><p>&nbsp;</p><p>答:<span style="color: #7b0c00; font-weight: bold;">多</span><span style="color: #7b0c00; font-weight: bold;">数也算。</span>只要含有西柚提取物或汁液,都可能带来相互作用;加工并不一定能消除影响。</p><p>&nbsp;</p><p><span style="color: #7b0c00; font-weight: bold;">2、和西柚错开几小时就安全了吗?</span></p><p>&nbsp;</p><p>答:<span style="color: #7b0c00; font-weight: bold;">未必。</span>因其为&ldquo;机制性抑制&rdquo;,影响可持续24&ndash;72小时,<span style="color: #7b0c00; font-weight: bold;">单纯错开时间并不可靠。</span></p><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;">&nbsp;</p><section style="text-align: center; margin: 10px 0% 0px; line-height: 0; box-sizing: border-box;"></section><section class="empty_paragraph" style="-webkit-tap-highlight-color: transparent; margin: 10px 0px 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-family: PingFang SC, system-ui, -apple-system, BlinkMacSystemFont, Helvetica Neue, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: 0.544px; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; color: #3e3e3e; font-size: 16px; background-color: #ffffff; text-align: center; line-height: 0;"></section><section style="-webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-family: PingFang SC, system-ui, -apple-system, BlinkMacSystemFont, Helvetica Neue, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; orphans: 2; text-align: justify; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; color: #3e3e3e; font-size: 16px; background-color: #ffffff; letter-spacing: 4px;"><section class="empty_paragraph" style="text-align: center;"></section><section class="empty_paragraph" style="-webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; text-align: center;"></section><section class="empty_paragraph" style="-webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; text-align: center;"></section></section><section style="margin: 8px 0% 16px; box-sizing: border-box;"><section style="border-width: 0px 0px 1px; border-style: solid; border-bottom-color: #ff8124; font-size: 12px; box-sizing: border-box;"><p style="text-align: center; margin: 0px; padding: 0px; box-sizing: border-box;">来源:央视网、湖北日报</p></section></section><section style="text-align: center; margin-top: 10px; margin-bottom: 10px; line-height: 0; box-sizing: border-box;"><section style="max-width: 100%; vertical-align: middle; line-height: 0; box-sizing: border-box;"></section></section><section style="text-align: center; margin: 10px 0% 0px; line-height: 0; box-sizing: border-box;"><section class="empty_paragraph" style="max-width: 100%; vertical-align: middle; line-height: 0; box-sizing: border-box;"></section></section></section><p style="display: none;">&nbsp;</p>    <!----></div>            

小鱼nice 发表于 2025-10-28 22:13:20

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海阔天空a 发表于 2025-10-28 22:28:05

震惊

乌哥 发表于 2025-10-31 18:58:11

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